Insulin Resistance
Insulin resistance is a condition, in which the body's cells do not respond normally to insulin. Insulin is a hormone produced by the pancreas, an organ located just behind the stomach. Insulin transports blood glucose to all the body's cells. When muscle, fat and liver cells stop responding normally to insulin, blood glucose levels remain high. To compensate, the pancreas creates more insulin, but the cells still do not respond to the insulin like they are suppose to.
Insulin resistance is considered to be a mechanism involved in the pathology of cardiovascular diseases. Also, if left untreated, type 2 or adult-onset diabetes can result. Type II diabetics account for almost one half of the patients who progress to kidney failure.
One of the growing worldwide health issues is obesity. This results in an increase of fat cells and causes insulin to work less effectively. Losing weight can help reduce and, in some cases, reverse insulin resistance. Also, drugs like metformin and ACE inhibitors reduce insulin resistance, and this may be a reason why these drugs are successful in treating cardiometabolic diseases.
Insulin resistance or metabolic syndrome
is an early disease that often leads to
type II diabetes and associated complications
Cardiometabolic Diseases
