Insulin Resistance
Insulin resistance is a condition in which the body's cells do not respond normally to insulin. Insulin is a hormone produced by the pancreas, an organ located just behind the stomach. Insulin transports blood glucose to all the body's cells. When muscle, fat and liver cells stop responding normally to insulin, blood glucose levels remain high. The pancreas creates more insulin to compensate, but the cells don't respond to the action of insulin like they are suppose to.
Insulin resistance is considered to be a mechanism involved in the pathology of cardiovascular diseases. Also, if left untreated, type 2 or adult-onset diabetes can result. One of the growing worldwide health issues is obesity. This results in an increase of fat cells and causes the insulin to work less effectively. Losing weight can reverse insulin resistance. Also, drugs like metformin and ACE inhibitors reduce insulin resistance, and this may be a reason why these drugs are successful in treating cardiometabolic diseases.
Insulin resistance or metabolic syndrome
is an early disease that often leads to
type II diabetes and associated complications
Cardiometabolic Diseases
